G Kluger Selected Research

rufinamide

9/2012	First long-term experience with the orphan drug rufinamide in children with myoclonic-astatic epilepsy (Doose syndrome).
7/2011	Low long-term efficacy and tolerability of add-on rufinamide in patients with Dravet syndrome.
2/2011	Epilepsy with myoclonic absences - favourable response to add-on rufinamide treatment in 3 cases.
2/2011	Refractory focal epilepsy in a patient with methylmalonic aciduria: case report on positive and long-lasting effect of rufinamide.
9/2010	Adjunctive rufinamide in Lennox-Gastaut syndrome: a long-term, open-label extension study.
5/2008	Rufinamide for generalized seizures associated with Lennox-Gastaut syndrome.

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G Kluger Research Topics

Disease

5	Seizures (Absence Seizure) 01/2018 - 05/2008
5	Epilepsy (Aura) 05/2017 - 01/2001
3	Lennox Gastaut Syndrome 02/2011 - 05/2008
2	Myoclonic Epilepsies (Myoclonic Encephalopathy) 09/2012 - 07/2011
2	Syncope (Fainting) 02/2011 - 05/2008
2	Partial Epilepsies (Epilepsy, Partial) 02/2011 - 02/2010
1	Inborn Genetic Diseases (Disease, Hereditary) 01/2016
1	Acidosis 02/2011
1	Epileptic Syndromes 02/2011
1	Methylmalonic acidemia 02/2011
1	Limbic Encephalitis (Paraneoplastic Limbic Encephalitis) 02/2011
1	Landau-Kleffner Syndrome 02/2010
1	Rolandic Epilepsy (Centrotemporal Epilepsy) 02/2010
1	Body Weight (Weight, Body) 04/2009
1	Sleepiness 05/2008
1	Vomiting 05/2008
1	Brain Diseases (Brain Disorder) 08/2007
1	Thyroid Diseases (Thyroid Disease) 08/2007
1	Stroke (Strokes) 01/2001
1	Ischemic Stroke 01/2001
1	Chickenpox 01/2001
1	Genetic Predisposition to Disease (Genetic Predisposition) 01/2001
1	Persistent Vegetative State (Vegetative State) 06/2000
1	Heterotopic Ossification (Ectopic Ossification) 06/2000
1	Coma (Comas) 06/2000

Drug/Important Bio-Agent (IBA)

6	rufinamide FDA Link 09/2012 - 05/2008
4	Anticonvulsants (Antiepileptic Drugs)IBA 05/2017 - 05/2008
2	Levetiracetam (Keppra)FDA LinkGeneric 01/2018 - 02/2010
1	Dihydrotachysterol (AT 10)IBA 01/2018
1	AutoantibodiesIBA 02/2011
1	12- (4'- azido- 2'- nitrophenoxy)dodecanoyl- coenzyme AIBA 02/2011
1	Topiramate (Topamax)FDA LinkGeneric 04/2009
1	AntibodiesIBA 08/2007
1	SteroidsIBA 08/2007
1	HLA Antigens (Human Leukocyte Antigens)IBA 01/2001
1	Vigabatrin FDA Link 01/2001
1	HLA-B51 AntigenIBA 01/2001
1	DNA (Deoxyribonucleic Acid)IBA 01/2001
1	Lamotrigine (Lamictal)FDA LinkGeneric 01/2001
1	SalicylatesIBA 06/2000
1	Botulinum Toxins (Botulinum Toxin)IBA 06/2000
1	Baclofen FDA LinkGeneric 06/2000
1	Alkaline PhosphataseIBA 06/2000

Therapy/Procedure

3	Therapeutics 09/2010 - 01/2001
1	Ketogenic Diet 01/2016
1	Off-Label Use 02/2011